The Autobots continue to work for NEST, now no longer in secret. But after discovering a strange artifact during a mission in Chernobyl, it becomes apparent to Optimus Prime that the United States government has been less than forthright with them.
After finding a host body in investigative reporter Eddie Brock, the alien symbiote must face a new enemy, Carnage, the alter ego of serial killer Cletus Kasady.