After Kick-Ass’ insane bravery inspires a new wave of self-made masked crusaders, he joins a patrol led by the Colonel Stars and Stripes. When these amateur superheroes are hunted down by Red Mist — reborn as The Mother Fucker — only the blade-wielding Hit-Girl can prevent their annihilation.
Though safely entombed in a crypt deep beneath the unforgiving desert, an ancient queen whose destiny was unjustly taken from her is awakened in our current day, bringing with her malevolence grown over millennia, and terrors that defy human comprehension.